Healthcare // Drug Delivery Devices
The global Radiotherapy
market is foreseen to grow by 5.7%, from USD 6.95 Billion in 2022 to USD 10.83
Billion in 2030. Technological advancements, increasing incidence of cancer
worldwide, awareness initiatives on the benefits of radiotherapy, growing use
of particle therapy for cancer treatment is to drive the market for the
upcoming forecast period. However, Inadequate healthcare infrastructure, shortage
of skilled oncologists and radiologists remains one factor hindering the market
growth over the anticipated period.
What Is Radiotherapy?
Radiotherapy, also known as radiation therapy, is a type of cancer treatment that uses high-energy radiation to destroy cancer cells. It works by damaging the DNA inside cancer cells, which prevents them from dividing and growing. Radiotherapy can be used alone or in combination with other cancer treatments, such as chemotherapy and surgery. In this essay, we will explore the basics of radiotherapy, its effectiveness in treating cancer, and the potential side effects.
Types of Radiotherapy
There are two main types of radiotherapy: external beam radiation therapy and internal radiation therapy. External beam radiation therapy involves using a machine outside the body to deliver high-energy radiation to the cancer site. This type of radiotherapy is the most common and can be used to treat almost any part of the body. Internal radiation therapy, also known as brachytherapy, involves placing a small amount of radioactive material inside the body near the cancer site. This type of radiotherapy is commonly used to treat prostate cancer, cervical cancer, and breast cancer.
Effectiveness of Radiotherapy
Radiotherapy can be a highly effective treatment for cancer. The effectiveness of radiotherapy depends on several factors, including the type and stage of cancer, the location of the cancer, and the overall health of the patient. Radiotherapy can be used as the primary treatment for some cancers or as part of a combination therapy. In some cases, radiotherapy may be used to shrink a tumor before surgery or to kill any remaining cancer cells after surgery. The goal of radiotherapy is to destroy cancer cells while minimizing damage to healthy cells.
Side Effects of Radiotherapy
Like any cancer treatment, radiotherapy can cause side effects. The side effects of radiotherapy depend on the location of the cancer and the amount of radiation delivered. Common side effects include fatigue, skin irritation, nausea, and diarrhea. These side effects are usually temporary and go away after treatment is complete. However, in some cases, radiotherapy can cause long-term side effects, such as infertility or an increased risk of developing a second cancer.
Radiotherapy is a powerful tool in the fight against cancer. It can be used alone or in combination with other cancer treatments to destroy cancer cells and improve patient outcomes. Although radiotherapy can cause side effects, most of these are temporary and can be managed with medication and other therapies. If you or a loved one has been diagnosed with cancer, talk to your doctor about whether radiotherapy is an appropriate treatment option.
The expansion of the radiotherapy market is being propelled by technological advancements and an increasing prevalence of cancer. The market is also being driven by a growing awareness of the advantages of radiotherapy and the amplified use of particle therapy in cancer treatment. However, the development of this market is being hindered by inadequate healthcare infrastructure, particularly in emerging economies, and a shortage of qualified oncologists and radiologists. Furthermore, the high cost of radiotherapy equipment and the complicated nature of radiotherapy treatment are anticipated to curb the growth of this market in the projected timeframe.
Radiotherapy Market Dynamics
Radiotherapy is gaining traction due to various initiatives aimed at creating awareness about its benefits. Conferences and symposia, organized in recent years, have emphasized spreading awareness about the advantages of radiotherapy for treating a wide range of cancers. For instance, the 6th Cancer World Congress, scheduled to be held in Portugal in September 2022, will focus on "Personalized Cancer Diagnosis and Therapy." In May 2022, the 5th Global Cancer Summit (GCS-2022) was held virtually with the theme "Living with cancer in the 21st century" by BioGenesis Health Cluster and Global Cancer Foundation.
These events provide a platform to raise awareness and provide training for oncologists and radiographers on radiotherapy procedures. The increased awareness about available radiotherapy procedures and their benefits is expected to boost the demand and adoption of radiotherapy devices.
Restraints in Radiotherapy Market
One of the restraints in the global radiotherapy market is the shortage of skilled oncologists and radiologists. Despite continuous technological advancements, the high standards required for effective radiotherapy can only be achieved and maintained by experienced specialists. However, the shortage of trained personnel and technical expertise is expected to hinder the implementation of advanced radiotherapy techniques. This scarcity of skilled and trained personnel results in many cancer patients missing out on effective radiotherapy procedures, particularly in developing and underdeveloped countries.
In the United States, the American Society of Clinical Oncologists (ASCO) reported that only 13,146 oncologists were engaged in active patient care in 2021. While some cities have an abundance of oncologists, approximately 32 million Americans reside in counties with no oncologists. According to ASCO, the shortage of oncologists is projected to surpass 2,200 by 2025. Similarly, this lack of skilled oncologists and radiologists is a challenge in several countries worldwide, affecting the adoption of oncology procedures.
Opportunities in Radiotherapy Market
One of the main drivers of the global market growth is the increasing public-private investments and funding for cancer research, which aims to improve the diagnosis and treatment of cancer. Recent investments in radiotherapy solutions by companies like Leo Cancer Care and government funding, such as the USD 45.5 million application for regional radiation treatment centers in Australia, offer potential growth opportunities for market players.
Challenges in Radiotherapy Market
However, a major challenge faced during radiotherapy procedures is the difficulty in visualizing tumors and distinguishing them from normal healthy tissues. Although advancements in ionizing radiation therapy for cancer treatment can help overcome this challenge, daily changes in tumor shape make it difficult to only radiate the cancerous growth without affecting the surrounding tissues. Radiologists often include a safety margin around the tumor and limit the radiotherapy dose range to minimize damage to healthy tissue. As a result, the number of treatment cycles required to eradicate tumorous cells increases, which raises the treatment costs for patients undergoing radiotherapy. Additionally, detecting tumor progression remains a clinical challenge, despite technological advancements in imaging techniques. Due to these challenges, oncologists prefer alternative treatment technologies like chemotherapy and conventional surgical procedures.
The global radiotherapy market is categorized into three technology segments: external beam radiotherapy, internal beam radiotherapy/brachytherapy, and systemic radiotherapy products. The external beam radiotherapy products segment includes linear accelerators, particle therapy systems, and conventional cobalt-60 teletherapy units. The internal beam radiotherapy/brachytherapy products segment comprises seeds, applicators, after loaders, and IORT systems. The linear accelerators or LINAC segment is further divided into conventional LINAC systems and stereotactic advanced electron/cobalt-60 LINAC systems, which include the CyberKnife, Gamma Knife, and TomoTherapy sub-segments.
In 2021, the cyberknife sub-segment within the stereotactic advanced electron/cobalt-60 linear accelerators segment accounted for the largest share of the global radiotherapy market. This was attributed to the continuous development of the CyberKnife system. For example, Accuray Incorporated launched the CyberKnife S7 System in June 2020, which is designed to deliver precise stereotactic radiosurgery and stereotactic body radiation therapy treatments. Additionally, several supply deals for the CyberKnife platform were made between 2018 and 2021 with various organizations such as Stanford University Medical Center, Swiss Medical Network, and Mercy Advances Cancer Care. These developments are expected to drive the adoption of the CyberKnife technology.
The external beam radiotherapy segment is also seeing growth due to initiatives such as conferences and symposia, which are raising awareness about the benefits of radiotherapy procedures for a range of cancers. The 6th Cancer World Congress, which is set to take place in Portugal in September 2022, has the theme of "Personalized Cancer Diagnosis and Therapy," while the 5th Global Cancer Summit was held virtually in May 2022 with the theme of "Living with cancer in the 21st century." These events and others like them play a crucial role in spreading awareness about the available radiotherapy procedures and their benefits, ultimately leading to increased demand and adoption of radiotherapy devices.
The Internal Beam radiotherapy market is divided into several applications, including prostate cancer, gynecological cancer, breast cancer, cervical cancer, penile cancer, and other cancers. In 2022, the prostate cancer segment emerged as the top application, capturing the highest market share. Prostate brachytherapy, which involves the use of both LDR and HDR brachytherapy, is an advanced treatment for prostate cancer. Globally, brachytherapy is increasingly being used to treat high-risk prostate cancer either alone or in combination with hormone therapy or EBRT. LDR brachytherapy, which delivers low-dose radiation and protects surrounding healthy tissues, is as effective as prostatectomy or EBRT. Additionally, brachytherapy obviates the need to monitor the prostate gland's movement, as the radioactive seeds implanted move with the gland.
The External Beam radiotherapy market is categorized into several procedures, including IGRT, IMRT, stereotactic therapy, particle beam therapy, and 3D-CRT. The particle therapy segment is predicted to experience the highest growth rate in the external beam radiotherapy market by procedures during the forecast year. This growth can be attributed to several factors, including the rising number of proton therapy centers worldwide, increasing research activities in radiation oncology with proton therapy systems, lower risks associated with proton beam therapy, and a longer lifespan of proton beam therapy systems (30 years or more) as compared to photon therapy systems (10 years).
The global radiotherapy market is segmented into five regions: North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa. The North American market is further divided into the US and Canada. In 2022, the US held the largest market share in North America, primarily driven by increasing awareness about radiotherapy, a rising geriatric population, government initiatives in the form of funds and grants for radiotherapy-related research and development, and an increasing incidence of various cancers.
In FY 2021, Siemens Healthineers AG became the leading player in the global market after acquiring Varian Medical Systems, Inc. in April 2021. The acquisition resulted in the company commanding the highest market share in the global radiotherapy market, mainly due to the broad product portfolio of Varian Medical Systems, Inc. and the combined sales and distribution capabilities of both companies. To enhance its footprint in the global market, the company focuses on both organic and inorganic growth strategies. Under Siemens Healthineers, Varian Medical Systems, Inc. introduced and received regulatory approvals for several products, including the ProBeam proton therapy system, ProBeam 360 with multi-room configuration, and Halcyon system, in the last three years (2019-2021). The company has also entered into several agreements, partnerships, collaborations, and contracts to expand its market presence.
For the purpose of this report, the global Radiotherapy market segmented on the basis of therapy type, technology, procedure, application, end user, and region:
Therapy Type Outlook:
On the basis of therapy type, the market is segmented into external beam radiation therapy, internal radiation therapy, systemic radiation therapy.
On the basis of Technology, the market is segmented into External Beam Radiotherapy, Internal Beam Radiotherapy/Brachytherapy, Systemic Radiotherapy. Further, External Beam Radiotherapy is segmented into Linear Accelerators, Conventional Cobalt-60 Teletherapy Units, Particle Therapy Systems. Further, Internal Beam Radiotherapy/Brachytherapy is segmented into Seeds, Afterloaders, Applicators, IORT Systems. Further, Systemic Radiotherapy is segmented into Iobenguane (I-131), Samarium-153, Rhenium-186 , Other Systemic Radiotherapy Products.
On the basis of Procedure, the market is segmented into External Beam Radiotherapy, Internal Beam Radiotherapy/Brachytherapy, Systemic Radiotherapy. Further, External Beam Radiotherapy is segmented into Image-guided Radiotherapy, Intensity-modulated Radiotherapy, Stereotactic Therapy, Particle Therapy, 3D Conformal Radiotherapy. Further, Internal Beam Radiotherapy/Brachytherapy is segmented into High-dose-rate Brachytherapy, Low-dose-rate Brachytherapy, Pulsed-dose-rate Brachytherapy. Further, Systemic Radiotherapy is segmented into Intravenous Radiotherapy, Oral Radiotherapy, Instillation Radiotherapy.
Figure 1 Radiotherapy Market By Procedure (Market Size And Forecast By Value - USD Million, 2022 & 2030)